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Smarter Flow, Cleaner Results

Discover Contamination-Free Flow

Get a free sample of Clippard’s non-contact isolation valves, customizable for your application, to eliminate contamination risk, reduce maintenance, and reliably handle harsh or pulpy media.


THREE Isolation Valve Types Available for Your FREE Sample. 

All valves manufactured in the USA | ISO 13485 Certified. 

Need additional help? Our application experts can help you specify the right fit based on your application. 

Quick explainer of the three types of isolation valves.

Diaphragm Valve

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Common Uses: Sample injection, analytical instruments (HPLC, LC-MS), cell culture control, and chemical dosing. 

Simply put: Controlling contamination in analytical instruments

Pinch Valve

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Common Uses: Blood analysis, particle suspensions, bioprocessing, chromatography sample loops, and peristaltic pump systems.  

Simply put: Zero percent external exposure

Gradient Valve

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Common Uses: Gradient HPLC, buffer mixing, stream splitting, and solvent selection. 

Simply put: Mixing multiple fluid streams

A diaphragm valve is a solenoid-operated media isolation valve using a PTFE diaphragm to separate the actuator from the fluid path. This design reduces internal volume, simplifies construction, and prevents contamination.
  • 100% PTFE wetted surfaces

  • Minimal dead volume

  • Fast 5–50 ms response

  • Compatible with corrosive media

A solenoid pinch valve controls flow through replaceable silicone tubing. Only the tubing contacts the fluid, creating a fully unobstructed flow path.
  • Zero dead volume flow path

  • Replaceable tubing for easy maintenance

  • Low power (1.0–7.2W, 12/24VDC)

  • No wetted metal surfaces

A compact multi-channel PTFE isolation valve that combines multiple 2-way valves in one body. Independent actuators allow precise mixing or splitting of fluid streams.
  • Independent Channel Control

  • Reduced internal volume

  • All-PTFE fluid path

  • Compact manifold design




A solenoid-operated media isolation valve using a PTFE diaphragm to separate the actuator from the fluid path. This design reduces internal volume, simplifies construction, and prevents contamination.

Key Benefits

  • 100% PTFE wetted surfaces
  • Minimal dead volume
  • Fast 5–50 ms response
  • Compatible with corrosive media

A solenoid pinch valve that controls flow through replaceable silicone tubing. Only the tubing contacts the fluid, creating a fully unobstructed flow path.

Key Benefits

  • Zero dead volume flow path
  • Replaceable tubing for easy maintenance
  • Low power (1.0–7.2W, 12/24VDC)
  • No wetted metal surfaces

A compact multi-channel PTFE isolation valve that combines multiple 2-way valves in one body. Independent actuators allow precise mixing or splitting of fluid streams.

Key Benefits

  • Independent channel control
  • Reduced internal volume
  • All-PTFE fluid path
  • Compact manifold design

Fill Out the Form to Request your FREE Isolation Valve Sample

🕒 Expect a follow-up within a few days to schedule your in-person delivery of the free sample. 

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