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Smarter Flow, Cleaner Results
Discover Contamination-Free Flow
Get a free sample of Clippard’s non-contact isolation valves, customizable for your application, to eliminate contamination risk, reduce maintenance, and reliably handle harsh or pulpy media. These features make them ideal for life science and lab automation systems.
Watch a quick explainer of each of the three options
Quick Selection Guide:
Which Challenge Are You Trying to Solve?
Contamination in analytical instruments → Diaphragm Valve
Zero percent external exposure → Pinch Valve
Need to mix multiple fluid streams → Gradient Valve
Need additional help? Our application experts can help you specify the right fit based on your application.
The Diaphragm, NIV series media isolation valve, is a solenoid-operated device that utilizes a flexible diaphragm to isolate the actuation mechanism from the fluid path. This unique, multifunctional valve stem results in a simplified design with fewer parts, longer life, and minimal dead volume.
Key Benefits:
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100% PTFE wetted surfaces - Zero contamination risk from metal contact
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Minimal dead volume design - Reduces sample waste and cleaning time
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Fast 5-50ms response - Precise control for automated protocols
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Corrosive media compatible - Handles aggressive chemicals safely
Primary Applications:
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Sample injection systems - Contamination-free reagent delivery
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Analytical instrument fluid paths - HPLC, LC-MS, spectroscopy
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Cell culture media control - Sterile fluid switching
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Chemical dosing systems - Precise reagent metering
Full technical data, configuration options, CAD files, & material certifications
Clippard’s NPV Series pinch valves are solenoid-operated devices designed to control the flow of liquids and gases using replaceable silicone tubing.
Unlike other valve types that may retain trace fluid, these valves ensure a completely unobstructed flow path with zero dead volume; only the inside of the tubing contacts the fluid.
Key Benefits - NPP Pneumatic Series:
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Unobstructed Flow Path - No cavities or dead volume
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Replaceable Tubing - Quick-change silicone tubing for easy maintenance and customization
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Low Power Consumption - Operates at 1.0–7.2W depending on the model; supports 12V or 24VDC
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High Cycle Life - Engineered for longevity and consistent performance
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No Wetted Metal Surfaces - All wetted areas are silicone tubing, minimizing contamination risks
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Compact and Versatile - Available in metric and imperial sizes with multiple mounting options
Primary Applications:
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Blood analysis systems - Cell counting, flow cytometry
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Particle suspension handling - No clogging or settling zones
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Bioprocessing - Cell culture, fermentation fluid control
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Sample loop filling - Injection systems for chromatography
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Peristaltic pump integration - Seamless tube-based systems
Tubing selection charts, configuration examples, & more application examples
NIV series multi-channel gradient valves feature multiple 2-way, normally-closed PTFE media isolation valves connected around a central body. This unique design provides a significant reduction in internal volume with enhanced mixing capabilities.
Each actuator operates independently, allowing for the flow of various media to be mixed or for one media to be split into multiple streams. These multi-channel gradient mixing valves are useful for solvent selection, stream splitting, flushing, and other automated applications.
Key Benefits - NPP Pneumatic Series:
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Independent channel control - Mix multiple fluids with precise ratios
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Reduced internal volume - Enhanced mixing efficiency
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All PTFE construction - Same contamination-free benefits as NIV series
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Compact multi-valve design - Space-efficient manifold configuration
Primary Applications:
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Gradient HPLC systems - Mobile phase mixing and selection
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Buffer preparation - Automated solution blending
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Stream splitting - Distribute a single source to multiple outlets
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Solvent selection - Automated fluid switching for analysis
Mixing calculations, flow charts, and configuration examples
